Z-Scores vs. LLR in NIPT: Decoding the Statistics Behind Prenatal Screening

Introduction Non‑Invasive Prenatal Testing (NIPT) has revolutionized prenatal screening by enabling the detection of common aneuploidies through a simple maternal blood sample. But behind every “high risk” or “low risk” result lies complex statistical modeling: most notably involving tools like Z‑scores and Log‑Likelihood Ratios (LLRs). While both aim to assess whether a fetus may have … Continue reading Z-Scores vs. LLR in NIPT: Decoding the Statistics Behind Prenatal Screening